Modules

ZFN (zinc-finger nuclease) and TALEN (transcription activator-like effector nuclease)

Off-target effects

In vitro gametogenesis and genome editing

Reversibility of genome editing

Germline therapy and Embryo Protection Act

Efficiency of transport of editing tools

Gene therapies and the defence against disease

PGD and germline therapy

Genome

RNA and DNA

In-utero gene therapy

In-vitro fertilisation

The experiment of He Jiankui

Genetic engineering methods

Genome editing and enhancement

Genetic editing of human embryos

Genome editing and basic research

On-target effects

Mosaicism

Germline therapy and safety considerations